The Sensitivity and Specificity of Chest X-ray in COVID-19 Patients Keeping HRCT as Gold Standard

Authors

  • Dr Uzma Margalla Hospital
  • Dr Nafeesa Margalla Hospital
  • Dr Ayesha Margalla Hospital
  • Dr Arooj Margalla Hospital
  • Dr Humaira
  • Dr Nain Margalla Hospital
  • Dr Manahil Rawalpindi Medical University
  • Dr Amna Al Nafees Medical College

Keywords:

covid 19, CXR, HRCT

Abstract

Objective: To determine sensitivity & specificity of chest X-ray in COVID-19, taking High-Resolution Computed Tomography as
gold standard.
Study Design: Cross-sectional study.
Place and Duration of Study: Radiology Deptt, Margalla Hospital, Taxila and Islamabad Diagnostic Centre, Wah. Two years
(February 2020 to February 2022).
Patients and Methods: The sample comprised 100 COVID-19 patients (Positive Polymerase chain reaction (PCR) test). Their HighResolution Computed Tomography (HRCT) was done which was considered a gold standard for diagnosing COVID-19. Their
Chest X-rays (CXR) were performed, and findings of both modalities were compared. Patients having respiratory tract symptoms
but PCR negative for COVID-19 were excluded.
Results: The research had 49 males & 51 females having a median (IQR) age of 46.50(35-55.75) years. The minimum & maximum
ages were 6 years and 83 years respectively. Among 100 PCR-positive patients, 29 were found normal on HRCT and 30 on CXR.
For moderate cases, the chest X-rays were 72% sensitive & 90.67% specific, with Positive Predictive Value (PPV), Negative Predictive
Value (NPV) & diagnostic efficacy of 72%,90.67% & 86% respectively. Similarly, other severity levels were assessed.
Conclusion: CXR has acceptable diagnostic accuracy for COVID-19 patients, especially with good sensitivity for moderate cases
and better specificity for severe cases. A portable chest radiograph might be regarded as an initial alternative imaging modality for
patients with COVID-19 signs and symptoms in remote areas.
Key words: COVID-19, CXR , HRCT
How to cite this article: Abdullah U, Tariq N, Rizwan A, et al. Diagnostic accuracy of chest x-ray in covid -19 patients taking highresolution computed tomography as gold standard. HMDJ. 2024; 04(01): 04-07. doi: 10.69884/hmdj.4.1.8943

 

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Author Biographies

Dr Uzma, Margalla Hospital

Head of Department of Radiology, Margalla Hospital, Taxila

Dr Nafeesa, Margalla Hospital

Head of Department of Gynaecology and Obstetrics, Margalla Hospital, Taxila

Dr Ayesha, Margalla Hospital

Dermatologist, Margalla Hospital, Taxila

Dr Arooj, Margalla Hospital

Department of Medicine, Margalla Hospital, Taxila

Dr Humaira

Department of Anatomy, Swat Medical College, Swat

Dr Nain, Margalla Hospital

Department of Surgery, Margalla Hospital, Taxila

Dr Manahil, Rawalpindi Medical University

4th Year MBBS, Rawalpindi Medical University, Rawalpindi

Dr Amna, Al Nafees Medical College

3rd Year MBBS, Al Nafees Medical College, Islamabad

Additional Files

Published

14-08-2024

How to Cite

Awan, U. A., Nafeesa Tariq, Ayesha Rizwan, Arooj Zahra, Humaira Ali, Nain Sukh, Manahil Tipu, & Amna Shoaib. (2024). The Sensitivity and Specificity of Chest X-ray in COVID-19 Patients Keeping HRCT as Gold Standard. HITEC Medical &Amp; Dental Journal, 4(1). Retrieved from https://hmdj.hitec-ims.edu.pk/hmdj/index.php/demo/article/view/16